Opening treatment guide...

Filler Dissolving | My Beauty Protocol

Correction

Filler Dissolving

Hyaluronidase Filler Dissolution

The simple version: Hyaluronidase Filler Reversal

Also known asHylenexVitraseAmphadase

Educational info only, not medical advice. Ask a qualified provider. Disclaimer · Terms

Hyaluronidase enzyme is injected to break down hyaluronic acid filler bonds.

Downtime: 1 week
Sessions: 1–3
Pain: Low
Cost per visit: Price level 2 of 5
Full course: 1–3 sessionsAsk the total price for all of them.
Results start: In 1–2 days
Results last: Permanent

Enzyme injections that dissolve hyaluronic acid filler.

Check first: Known allergy to hyaluronidase or bee stings.

Will it work for me?

What people use it for

Tap one to see how it helps.

How do the brands differ?

In no special order. Ask which one they use, and why.

3 brands

Ask your provider

Which one do you use, and why that one for me?
What is the total price, and what does it include?
What side effects do you see most with it, and what do you do about them?

Before and after your visit

Plan it around your lifeMakeup, sun, workouts — see what fits around your treatment.

The visit

Duration: 15–30 minutes
Total course: Typically completed within one day to a few weeks.
Session interval: 1–2 weeks

What to expect, and what to avoid

Recovery

1–2 days of swelling; bruises can last a week

May look swollen

1 week

Avoid sun

24 hours

No makeup

12 hours

No sweat or heat

24 hours

Other aftercare

Don't touch, rub or press the area for a few hours

Your provider may give you different timing.

Day by day

Before your visit: ask when to start
- Inform your provider of any allergies, especially to bee stings, as this can indicate a higher risk of allergy to some types of hyaluronidase.
- Come with clean skin: no makeup or lotion
1 week before
Stop aspirin, ibuprofen, fish oil and vitamin E for 1 week before, if your doctor agrees
Right after your visit
- No alcohol for 24–48 hours
- No fish oil or vitamin E for 24–48 hours
- Avoid hard exercise, heat and heavy sweating for 24 hours
After your visit
- Use a cold pack for swelling in the first few hours
- You may gently massage the area if instructed by your provider to help distribute the enzyme.
- The filler begins to break down almost immediately, with visible reduction in volume within 24-48 hours. Swelling and redness are most prominent in the first few hours and typically subside within 1-2 days. Any bruising may take up to a week to fully resolve. Results start to show in 1–2 days.

Side effects, and who should wait

Who may want to think twice

Known allergy to hyaluronidase or bee stings
Active skin infection in the treatment area
Pregnancy and breastfeeding (as a precaution)
Certain autoimmune disorders

Possible side effects

Common

Swelling
Bruising
Redness
Tenderness or pain at the injection site
Itching

Less common

Allergic reaction (ranging from mild rash to severe anaphylaxis)
Infection
Temporary hollowing or volume loss of the body's own natural hyaluronic acid (which usually regenerates)
Angioedema (deep skin swelling)

Your own risks may differ. Ask a qualified provider.

How it works, and common myths

Hyaluronidase enzymatically cleaves hyaluronic acid molecules, converting the filler gel into a liquid for natural bodily clearance.

A little more technical

An enzyme called hyaluronidase is injected to rapidly break down the chemical bonds of hyaluronic acid filler, turning the gel into a liquid that the body can naturally clear away.

Hyaluronidase is an endoglycosidase enzyme that catalyzes the hydrolysis of hyaluronic acid. It cleaves the glycosidic bonds of the HA polymer, reducing its viscosity and allowing the fragmented chains to be absorbed and metabolized by the body.

Material: Hyaluronidase Enzyme; A synthesized protein that immediately attacks and breaks the molecular bonds of hyaluronic acid gel.
Mechanism category: Enzymatic Hydrolysis; Rapidly liquefies hardened or migrated filler so your body's lymphatic system can naturally flush it out.
Common device / product names: Hylenex · Vitrase · Amphadase
Clinical descriptor: Hyaluronidase Filler Dissolution

Common myths

Your next step

Take it to your consult

Your questions, cost and timing on one page.

Open Consult Kit

Compare with similar treatments

Side by side. The choice is yours.

Often explored alongside this treatment

Botox Complication Care

Care for problems after Botox or Dysport, like a drooping eyelid or uneven brows

Downtime: Same day
Pain: Low
Cost: Price level 2 of 5

Laser Side-Effect Care

Care for burns, dark spots or scars after a laser treatment

Downtime: Same day
Pain: Varies
Cost: Price level 2 of 5

Tattoo Darkening Treatment

Laser treatment for tattoo ink that turned darker during laser removal

Downtime: 3 days
Pain: Low to medium
Cost: Price level 3 of 5

Open full comparison(4)

Find Filler Dissolving near you

Opens in Maps

A listing is not an endorsement. Check any provider yourself.

Spotted something wrong or out of date?